
Dirt, which focuses on the complex relationship between the entertainment industry and United States tabloid magazines, airs on the FX Network and is executively produced by Cox and her husband, David Arquette.
Since Friends, Dirt is considered Cox's most high-profile project. Aniston, however, has gone on to star in recent films such as Derailed and The Break-Up. The episode, in which Aniston will play Cox's rival, is scheduled to end the drama's opening series, airing on March 27, 2007.
Source: The Celebrity Cafe